labquiet_amy said:The intervention that works is boring and well evidenced: resistance training two to three times a week at a genuine effort, protein at 1.4 to 2.0…
I read this differently from labquiet_amy, on substance rather than tone. I think this board over-worries about lean mass. Some lean loss is obligatory — you need less muscle to move a smaller body, and preserving mass you no longer need is not a health outcome. The question is whether strength and function held, and mine did.
Ask again with the specifics and you will get a better answer than this one.
nick_newbie said:I lifted three times a week throughout and still lost lean mass.
Sharing my comprehensive lab data relevant to lean mass:
| Biomarker | Baseline | Month 3 | Month 6 | Month 9 |
|---|---|---|---|---|
| Weight (lbs) | 252 | 262 | 212 | 202 |
| A1C (%) | 6.7 | 6.2 | 5.7 | 5.4 |
| hsCRP (mg/L) | 7.0 | 5.0 | 1.5 | 0.8 |
| Triglycerides | 212 | 172 | 112 | 92 |
Protocol: Semaglutide 1.7mg/wk, resistance training 3x/week, protein 1.2g/kg/day.
The improvements in lean mass are clearly reflected in these numbers. The inflammatory marker reduction (hsCRP) is particularly striking.
Dr.BariatricHTX said:I think this board over-worries about lean mass.
Body composition tracking via bioimpedance on lean mass (InBody scan every 3 months):
| Metric | Baseline | Month 3 | Month 6 | Month 9 |
|---|---|---|---|---|
| Skeletal Muscle (lbs) | 73 | 73 | 67 | 75 |
| Body Fat (lbs) | 85 | 73 | 63 | 47 |
| Body Fat % | 43% | 31% | 28% | 22% |
| Visceral Fat (cm²) | 150 | 125 | 85 | 60 |
Note: skeletal muscle mass dipped initially then recovered with consistent resistance training + high protein. The visceral fat reduction is where the metabolic magic happens.
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Browse GL BiochemOne thing that is still open after raj_cambridge’s answer:
What fraction of loss being lean mass is actually normal, because the numbers quoted here range from 10% to 40% and cannot all be right?
Reporting back.
Second scan under matched conditions, six months apart, same time of day: the lean number came back nearly a kilo higher than the panic scan. Strength was up throughout.