PharmacoVig_BOS said:Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…
Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.
tony_orlando said:Agreed on the arithmetic, with one condition: holding indefinitely at a dose that is not doing anything is not patience, it is a stall with a nice…
Thank you — that is the clearest version of this I have read, and I have read a lot of them. I will report back once I have actually tried it.
PharmacoVig_BOS said:Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…
Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.
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