Dr.PeteFamMed said:PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.
My labs after 9 months on glycaemic control: A1C 5.4%, fasting glucose 89 mg/dL, fasting insulin 8 uIU/mL. My endo says these are "textbook perfect."
For context, my baseline A1C was 7.3% and fasting glucose was 114 mg/dL. The improvement has been dramatic and consistent.
AmyNC_wife said:Fasting glucose improved within weeks and my HbA1c barely moved for three months, which I now understand and did not at the time.
Fasting insulin is the lab my functional medicine doctor cares about most for glycaemic control: it's a much earlier marker of metabolic dysfunction than glucose or A1C.
My fasting insulin: 28 → 12 → 5 uIU/mL over 9 months. Target is <7. By the time your fasting glucose is elevated, your insulin has been elevated for YEARS trying to compensate.
Ask your doctor to include fasting insulin in your bloodwork panel. It's cheap (~$20) and incredibly informative.
amsterdam_pete said:My labs after 9 months on glycaemic control: A1C 5.4%, fasting glucose 89 mg/dL, fasting insulin 8 uIU/mL.
Complete metabolic panel trending on glycaemic control — sharing because comprehensive data helps everyone:
| Test | Baseline | Month 3 | Month 6 | Month 12 |
|---|---|---|---|---|
| Glucose (fasting) | 130 | 100 | 90 | 84 |
| Insulin (fasting) | 26 | 14 | 10 | 7 |
| HOMA-IR | 4.5 | 3.6 | 1.8 | 1.4 |
| Uric Acid | 8.3 | 7.0 | 5.7 | 5.1 |
The insulin resistance improvement (HOMA-IR) is what my endo focuses on most. Going from 4.5 to near 1.0 is a metabolic transformation.
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Shop Reference StandardsFollowing on from tyler_CSCS — and this may be the naive question:
Was that from a primary source or from a summary of one?
BariatricNurseD said:Complete metabolic panel trending on glycaemic control — sharing because comprehensive data helps everyone: Test Baseline Month 3 Month 6 Month 12…
Glycemic variability as the key metric for glycaemic control success: my coefficient of variation (CV) on CGM dropped from 35% to 21%. Target is <36%, with <30% being ideal.
Why this matters more than average glucose: large glucose swings cause oxidative stress, endothelial damage, and promote advanced glycation end-products (AGEs). A flat glucose line at 95 mg/dL is metabolically healthier than oscillating between 60 and 160, even if the average is the same.