emily_PDX said:Do it in two steps and it stops being confusing.
Bacteriostatic water quality matters for dosing arithmetic reconstitution. Not all BAC water is created equal:
- Should contain 0.9% benzyl alcohol as preservative
- Must be sterile and pyrogen-free
- Should come in a sealed, intact vial
- Check expiration date — yes, BAC water expires
- Store at room temperature, protected from light
I buy from a reputable medical supply company, not Amazon marketplace sellers. The $3 savings isn't worth the infection risk from unverified BAC water.
A narrower follow-up, since the general answer is now clear:
How to check the arithmetic without trusting a website calculator, since three calculators gave me three answers?
BiostatsBrad said:Bacteriostatic water quality matters for dosing arithmetic reconstitution.
Reconstitution tip for anyone mixing dosing arithmetic from lyophilized powder: use bacteriostatic water, NOT sterile water. The benzyl alcohol in BAC water preserves multi-dose vials for up to 28 days.
Inject the water slowly down the side of the vial. NEVER shake — gentle swirling only until fully dissolved. Should be crystal clear with no particles.
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Browse GL BiochemOP back with an update, since a thread like this is useless without one.
Resolved. I wrote mg, ml and mg/ml on the vial in marker and did the division in that order, and the two of us now get the same number every time.
Dr.AddMedPHL said:Reconstitution tip for anyone mixing dosing arithmetic from lyophilized powder: use bacteriostatic water, NOT sterile water.
Agreed, and it is worth saying that rounding to the nearest whole unit is usually acceptable at maintenance doses and is not acceptable at the bottom of a ladder, where one unit can be a fifth of the intended dose.