rachel_ABQ said:It helps to ask what evidence would change your mind before you look at any.
No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.
dan_philly said:The phase 2 numbers were about 24% mean weight loss at 48 weeks on the top dose, with the curve still descending at the end of the study.
Genuinely useful, thank you. I had the facts and not the framework. Adding it to my notes with a link back to this thread.
rachel_ABQ said:It helps to ask what evidence would change your mind before you look at any.
This is where I part company with the consensus forming above. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.
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Browse GL BiochemOne concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.