Dr.ObesityLA said:Read four things before the headline number.
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
Dr.EndoIndy said:The phase 2 numbers were about 24% mean weight loss at 48 weeks on the top dose, with the curve still descending at the end of the study.
Thank you — that is the clearest version of this I have read, and I have read a lot of them. Taking it to my next appointment.
Dr.ObesityLA said:Read four things before the headline number.
I read this differently from Dr.ObesityLA, on substance rather than tone. I would add the less popular caveat: these trial populations under-represented several groups, older adults and the highest BMI categories among them. The results probably generalise, and "probably" should be stated as an assumption rather than dropped.
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Browse GL BiochemOne concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.