PharmacoVig_BOS said:Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…
That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.
laura_annarbor said:Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.
Bookmarking. The distinction being drawn above is the one nobody else makes.
PharmacoVig_BOS said:Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…
I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.
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View ResultsOne concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.