May 20, 2026 at 3:52 AM#16
Dr.CardioMD said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Adding a me-too, because a thread of one person's experience is not much use. Nothing to add that would improve it.
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May 20, 2026 at 9:52 AM#17
One thing that is still open after HPLC_Greg’s answer:
What did you change at the same time, and can you separate the two now?
41 14mike.trainer_LA, sarah_nash92, FitDadDave and 38 others
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May 20, 2026 at 3:52 PM#18
kate.chem said:Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…
This is where I part company with the consensus forming above. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.
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Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsMay 20, 2026 at 9:52 PM#19
kate.chem said:Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…
Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.
Last edited: May 21, 2026 at 1:52 AM
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