sean_dublin said:Mostly the deficit, and the useful part of that answer is that it is testable.
Agreed, though "tolerable" needs defining. A dose you tolerate by eating almost nothing is not tolerated, it is being paid for somewhere else — usually in lean mass, sometimes in adherence three months later.
dan_philly said:The dose-response is real but shallow at the top.
Saving this. It is the first explanation that did not require me to already understand it. I will report back once I have actually tried it.
sean_dublin said:Mostly the deficit, and the useful part of that answer is that it is testable.
I will push back on the "any working dose is fine" framing. The maintenance evidence sits overwhelmingly at the top studied dose, and the extension data shows regain tracking dose reduction rather than tracking stopping. Holding low is reasonable; pretending it is evidentially equivalent is not.
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View ResultsThe figures, for anyone assembling their own picture. Worth checking before concluding it is the drug: ferritin, B12, TSH, and total intake for three honest days. Two of those four explain most cases.
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