amsterdam_pete said:Advanced lipoprotein testing on the lipid panel — going beyond standard lipid panel: Marker Baseline Month 8 Clinical Meaning LDL-P 1668 968 Particle…
Careful with treating an unchanged LDL-C as a failure. If ApoB and triglycerides both fell, the particle picture improved regardless of what the calculated LDL says.
Happy to go further on any of that.
dan_philly said:Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.
Before/after bloodwork compilation for the lipid panel — everything in one place for those who want comprehensive data:
| Category | Marker | Before | After 13mo | Change |
|---|---|---|---|---|
| Metabolic | A1C | 7.2% | 5.5% | ⬇️ 1.4% |
| Metabolic | Fasting Glucose | 121 | 90 | ⬇️ 26 |
| Lipids | LDL | 149 | 93 | ⬇️ 41 |
| Lipids | Triglycerides | 221 | 111 | ⬇️ 111 |
| Inflammation | hsCRP | 6.5 | 0.9 | ⬇️ 5.0 |
Every single metabolic marker improved. This is why I'm a believer in this therapy.
Dr.SleepRoch said:Careful with treating an unchanged LDL-C as a failure.
Omega-3 index improvement on the lipid panel: often overlooked but my omega-3 index went from 3.8% to 7.8% over 11 months. I supplemented with 2g EPA+DHA daily.
This matters because omega-3s are anti-inflammatory and cardioprotective, complementing the GLP-1 benefits. Target omega-3 index is >8%. Combined with the triglyceride reduction from the medication, my lipid profile is the best it's been in decades.
Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsOne thing that is still open after wanda_boise’s answer:
What did you change at the same time, and can you separate the two now?
Closing the loop on my own question.
For the archive: it took about six weeks rather than the two I expected, and the difference between those two numbers was the whole of my problem.